Korelasi Lingkar Pinggang dengan Kadar Gula Darah Puasa, Kadar Trigliserida, dan Tekanan Darah pada Mahasiswa Fakultas Kedokteran Universitas HKBP Nommensen

Ervina Julien Sitanggang

Abstract


Introduction: Cardiovascular disease is the number one cause of death globally with an incidence of adolescents and young adults in Indonesia as many as 153.705 cases. Central obesity is associated with the risk of cardiovascular disease due to increase in fasting blood glucose levels, cholesterol and triglyceride levels, and blood pressure. Aims: to determine the correlation between waist circumference and fasting blood glucose levels, triglyceride levels, and blood pressure in young adults. Method: This analytic study with a cross-sectional approach involved 53 young adult subjects (18-25 years old). Waist circumference is measured using a tape measure. Blood sugar and triglyceride levels were measured using Cobas® 6000 analyzer machine from blood samples of subjects after fasting for 8-12 hours. Blood pressure data are obtained by measurement using aneroid sphygmomanometer. Results: In this study, the mean waist circumference of the research subjects was 77,4 cm. No correlation was found between waist circumference and fasting blood sugar levels (p = 0,159). However, a positive correlation was found between waist circumference and triglyceride levels (p = 0,008; r = 0,332), between waist circumference and systolic blood pressure (p = 0,049; r = 0,230), and between waist circumference and diastolic blood pressure (p = 0,017; r = 0,293). Conclusion: waist circumference is positively correlated with triglyceride levels and blood pressure, but does not correlate with fasting blood sugar levels.


Keywords


waist circumference; fasting blood glucose levels; triglyceride levels, blood pressure

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References


World Health Organization. Cardiovascular Diseases [Internet]. [cited 2019 Oct 30]. Available from: https://www.who.int/health-topics/cardiovascular-diseases/#tab=tab_1

Pusat Data dan Informasi Kementerian Kesehatan RI. Situasi Kesehatan Jantung. Kementerian Kesehatan RI. 2014.

Yang HK, Han K, Kwon HS, Park YM, Cho JH, Yoon KH, et al. Obesity, metabolic health, and mortality in adults: A nationwide population-based study in Korea. Sci Rep [Internet]. 2016;6(July):1–10. Available from: http://dx.doi.org/10.1038/srep30329

Tchernof A, Després JP. Pathophysiology of human visceral obesity: An update. Physiol Rev. 2013;93(1):359–404.

Harbuwono DS, Pramono LA, Yunir E, Subekti I. Obesity and central obesity in indonesia: Evidence from a national health survey. Med J Indones. 2018;27(2):53–9.

Sone H, Tanaka S, Tanaka S, Iimuro S, Oida K, Yamasaki Y, et al. Serum level of triglycerides is a potent risk factor comparable to LDL cholesterol for coronary heart disease in Japanese patients with type 2 diabetes: Subanalysis of the Japan Diabetes Complications Study (JDCS). J Clin Endocrinol Metab. 2011;96(11):3448–56.

Van Gaal LF, Mertens IL, De Block CE. Mechanisms linking obesity with cardiovascular disease. Nature. 2006;444(7121):875–80.

Grundy SM, Neeland IJ, Turer AT, Vega GL. Waist circumference as measure of abdominal fat compartments. J Obes. 2013;2013.

World Health Organization. Waist Circumference and Waist-Hip Ratio Report of a WHO Expert Consultation [Internet]. World Health Organization. 2008. Available from: pps.who.int/iris/bitstream/handle/10665/44583/9789241501491_eng.pdf?sequence=1

Sweeney MET. What are the ATP III guidelines classification of triglycerides? [Internet]. 2019. Available from: https://www.medscape.com/answers/126568-15893/what-are-the-atp-iii-guidelines-classification-of-triglycerides

Bell K, Twiggs J, Olin BR. Hypertension: The Silent Killer: Updated JNC8 Guideline Recommendations Associate Clinical Professor of Pharmacy Practice, Drug Information and Learning Resource Center. Alabama Pharm Assoc. 2015;1–8.

Soelistijo SA, Novida H, Rudijanto A, Soewondo P, Suastika K MA. Konsensus Pengelolaan dan Pencegahan Diabetes Melitus Tipe 2 di Indonesia 2015.

Kim D, Hou W, Wang F, Arcan C. Factors affecting obesity and waist circumference among US adults. Prev Chronic Dis. 2019;16(1):1–9.

Mihardja L, Soetrisno U. Prevalence and Determinant Factors for Overweight and Obesity and Degenerative Diseases Among Young Adults in Indonesia. J ASEAN Fed Endocr Soc. 2012;27(1):77–81.

Kriketos AD, Greenfield JR, Peake PW, Furler SM, Denyer GS, Charlesworth JA, et al. Inflammation, insulin resistance, and adiposity: A study of first-degree relatives of type 2 diabetic subjects. Diabetes Care. 2004;27(8):2033–40.

Soelistijo SA, Novida H, Rudijanto A, Soewondo P, Suastika K, Manaf A. Konsensus Pengelolaan dan Pencegahan Diabetes Melitus Tipe 2 di Indonesia 2015. PERKENI; 2015. 1-58.

Soewondo P, Pramono LA. Prevalence, characteristics, and predictors of pre-diabetes in Indonesia. Med J Indones. 2011;20(4):283–94.

Nurdamayanti ME, Elon Y. Korelasi Indeks Massa Tubuh dengan Kadar Trigliserida. 2019;3(2):52–7.

Miller M, Stone NJ, Ballantyne C, Bittner V, Criqui MH, Ginsberg HN, et al. Triglycerides and cardiovascular disease: A scientific statement from the American Heart Association. Circulation. 2011;123(20):2292–333.

Bawazier LA, Buntaran S, Sianipar W, Kekalih A. Blood Pressure Profile of Young Adults at the Faculty of Medicine Universitas Indonesia. Acta Med Indones. 2019;51(1):54–8.

Putri AFC. Korelasi Lingkar Pinggang dan Rasio Lingkar Pinggang-Panggul Terhadap Kadar Glukosa Darah Puasa Pada Mahasiswa dan Mahasiswi Kampus III Universitas Sanata Dharma Yogyakarta [skripsi]. Universitas Sanata Dharma Yogyakarta. 2013.

Kwon HW, Lee SM, Lee JW, Oh JE, Lee SW, Kim SY. Association between volume and glucose metabolism of abdominal adipose tissue in healthy population. Obes Res Clin Pract [Internet]. 2017;11(5):133–43. Available from: http://dx.doi.org/10.1016/j.orcp.2016.12.007

Sari DI. Korelasi Lingkar Pinggang dan Rasio Lingkar Pinggang Panggul terhadap Kadar Trigliserida Pada Mahasiswi dan Mahasiswa di Kampus III Universitas Sanata Dharma Yogyakarta [skripsi]. Universitas Sanata Dharma Yogyakarta. 2012.

Eckel RH. The Metabolic Syndrome. In: Harrison’s Principles of Internal Medicine. Eighteenth. United States: The McGraw-Hill Companies; 2012. p. 1994.

Sumayku IM, Pandelaki K, Wongkar MCP. Hubungan Indeks Massa Tubuh Dan Lingkar Pinggang Dengan Tekanan Darah Pada Mahasiswa Fakultas Kedokteran Universitas Sam Ratulangi. e-CliniC. 2014;2(2).

Setiawan AH, Hastuti J, Rahmawati NT. Hubungan Antara Lingkar Pinggang, Lingkar Perut dan Lingkar Lengan Atas dengan tekanan Darah Sistolik dan Diastolik pada Mahasiswa di Daerah Istimewa Yogyakarta [skripsi]. Universitas Gadjah Mada. 2015.

White BA, Porterfield SP. Endocrine and Reproductive Physiology. 4th ed. Philadelphia: Elsevier; 2015. 71.




DOI: https://doi.org/10.33854/heme.v3i2.583

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