Alveolar Soft Part Sarcoma (ASPS) Dinding Dada pada Laki-Laki Usia Tua: Kasus Jarang

Rini Purnama Sari, Aswiyanti Asri, Hera Novianti

Abstract


Pendahuluan: Alveolar soft part sarcoma (ASPS) adalah jenis sarkoma yang jarang terjadi dan mencapai <1% dari semua subtipe sarkoma jaringan lunak. Tumor ini jarang terjadi setelah usia 50 tahun dan dibawah 5 tahun, namun ASPS dapat terjadi pada usia berapa saja dengan insiden puncak pada rentang usia 15-35 tahun. Laporan Kasus: Kami melaporkan kasus seorang laki-laki berusia 58 tahun datang dengan keluhan benjolan di dada sejak 3 bulan sebelum masuk rumah sakit. Pasien tidak mengetahui adanya benjolan pada dada sebelumnya, benjolan disadari pasien saat mengeluhkan nyeri pada dada dalam 3 bulan ini. Pemeriksaan fisik regio toraks, tampak massa di regio sternum dengan konsistensi kenyal padat, batas tidak tegas, ukuran 6x5x1,5cm. Hasil CT-scan toraks di dapatkan kesan soft tissue tumor dinding dada dengan destruksi sternum. Hasil histopatologi adalah Alveolar Soft Part Sarcoma. Kesimpulan: Diagnosis ASPS harus didasarkan pada temuan klinis, radiologis dan histopatologis.


Keywords


alveolar soft part sarcoma, soft tissue, pseudoalveolar

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References


Paoluzzi L, Maki RG. Diagnosis, prognosis, and treatment of alveolar soft-part sarcoma a review. JAMA Oncology Review. 2018;E1-E7

Weiss SW and Goldblum JR. Enzinger and weiss's soft tissue tumours. 6th edition.Philadelphia.Elsevier.2014:1070–9.

Jambhekar, NALadanyl M. Alveolar soft part sarcoma. In: Fletcher CDM, Unni KK, Mertens F. Editors. World health organization classification of tumours pathology and genetics of tumours of soft tissue and bone 5th edition. IARC Pres. 2020:297–99.

Silas, O.A., Adoga, A.A., Manasseh, A.N. et al. Persistent alveolar soft-part sarcoma with liver metastasis: a case report. J Med Case Reports. 2010; 4(233):1–4.

D Anggraini. Analysis of Alpha Fetoprotein Levels in Hepatocellular Carcinoma Patients in West Sumatera, Indonesia. In: International Journal of Medical Science and Clinical Invention, 2020.7 (7), 4879-4881

Horvai Andrew. High yield pathology bone and soft tissue pathology. 1st edition. Elsevier. 2012:426–27.

Kayton ML., Meyers P., Wexler LH., Gerald WL., LaQuaglia MP. Clinical presentation, treatment, and outcome of alveolar soft part sarcoma in children, adolescents, and young adults. J Pediatr Surg 2006;41:187–93.

Folpe Andrew L, Inwards Carrie Y. Bone and Soft Tissue Pathology. 1st edition. Elsevier. 2010:13–14.

Dodd Leslie G, Bui Marilyn M. Atlas of soft tissue and bone pathology with histologic, cytologic, and radiologic correlations. Demos medical. 2015:177–80.

Ju Hyeong Uk, Seo Kwang Won, Jegal Yangjin , Ahn 1 Jong-Joon, Lee Young Jik, Kim Young Min, Oak Chulho, Ra Seung Won. A Case of Alveolar Soft Part Sarcoma of the Pleura. J Korean Med Sci.2013;28:331–335.

Chatchai Pruksapong, Kantang Satayasoontorn, Alveolar soft part sarcoma of flexure tendon. Journal of Surgical Case Reports. 2017;12:1–4 .

Abdoulwahab A M, Koini M, Souna B.S, Zirbine A.S, Akambi S.K, Konguise Z. Alveolar Soft Tissue Sarcoma: A Case Report and Literature Review. Open Journal of Orthopedics.2017;7:408–413.

Akhtar Kafil, Anees Afzal. Alveolar soft part sarcoma: A rare cytological impression. IJCR. 2016;1(1).

Argani P., Lal P., Hutchinson B., Lui MY., Reuter VE., Ladanyi M. Aberrant nuclear immunoreactivity for TFE3 in neoplasms with TFE3 gene fusions: a sensitive and specific immunohistochemical assay. Am J Surg Pathol. 2003; 27: 750-61

Lindberg Matthew R, Lucas David, Gardner Jerad M, Cassarino David S, Kandi Stallings-Archer. Diagnostic pathology soft tissue tumors. 2nd edition. Elsevier. 2016: 678–81.

Orbach D., Brennan B., Casanova M., et al. Paediatric and adolescent alveolar soft part sarcoma: a joint series from European cooperative groups. Pediatr Blood Cancer 2013; 60:1826–1832.

Miettinen markku. Modern soft tissue pathology tumors and non-neoplastic conditions. Cambridge University Press. 2010:930 – 938

Gulwani H. Paraganglioma. 2021. Available at:https://www.pathologyoutlines.com/topic/mediastinumparaganglioma.html

Neuville A., Chibon F., Choindre JM. Grading of soft tissue sarcomas: from histological to molecular assessment. Pathology. 2014;46(2):113–120.

Coindre JM. Grading and staging sarcomas. In: Fletcher CDM., Bridge JA., Hogendoorn PCW., Mertens F. Editors. World health organization classification of tumours pathology and genetics of tumours of soft tissue and bone 4th edition. IARC Pres.2013:.17–18.

AS Suarfi, D Anggraini, N Nurwiyeni.Gambaran Histopatologi Tumor Ganas Payudara di Laboratorium Patologi Anatomi RSUP M. Djamil Padang Tahun. In: Health and Medical Journal. 2019. 1 (1), 07-14

Pennacchioli E., Fiore M., Collini P., et al. Alveolar soft part sarcoma: clinical presentation, treatment, and outcome in a series of 33 patients at a single institution. Ann Surg Oncol 2010; 17:3229–3233.




DOI: https://doi.org/10.33854/heme.v5i2.1274

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