A CLINICAL AND RADIOGRAPHIC ASSESSMENT OF THE EFFICACY OF THE LESION STERILIZATION AND TISSUE REPAIR TECHNIQUE (LSTR) IN PRIMARY TEETH

Natasha Gamasita, Indra Bramanti, Aloysia Supartinah Santoso, Rifani Rifani, Yunirahmilia Yunirahmilia

Abstract


Introduction: Pulp infection in primary teeth is a frequent case found in the clinic and requires endodontic treatment. Root canal preparation of primary teeth is quite difficult because of the anatomic variations of the roots and the need to manage children’s behaviour during the treatment. The short and non-invasive treatment that is preferable for pediatric patients is lesion sterilization and tissue repair (LSTR) technique. Aim: This article aims to evaluate the efficacy of LSTR treatment in deciduous teeth. Methods: Electronic databases including PubMed and Google scholar were searched using PICO keywords. Relevant articles only in the English language and full text (in vivo studies and case reports) published from Januari 2013 to Juny 2023 were selected. Result: According to the collected information there were thirteen articles included in the inclusion criteria. LSTR technique in primary teeth has shown excellent rates of clinical success and good radiographic results. Conclusion: LSTR can be considered as a treatment option for pulpally involved primary teeth.

Keywords


antibiotic paste; lesion sterilization and tissue repair; primary teeth; tooth infection

References


Arangannal P, Muthiah G, Jeevarathan J, Sankar P. Lesion sterilization and tissue repair in nonvital primary teeth: an in vivo study. Contemp Clin Dent 2019 ; 10(1):31-35.

Shankar K, Ramkumar H, Dhakshinamoorthy S, Paulindraraj S, Jayakaran TG, Bommareddy CS. Comparison of modified triple antibiotic paste in two concentrations for lesion sterilization and tissue repair in primary molars: an in vivo interventional randomized clinical trial. Int J Clin Pediatr Dent 2021; 14(3):388-392.

Parakh K, Kothari S, Daga P, Harsha GVD, Sarda R, Tamrakar A. Lesion sterilization and tissue repair therapy using GAM antibiotic paste: A series of cases. International Journal of Health Sciences 2021; 5(2):453–458.

Sain S, Reshmi J, Anandaraj S, et al. Lesion sterilization and tissue repair-current concepts and practices. Int J Clin Pediatr Dent 2018; 11(5):446-50.

Arksey H, O’Malley L. Scoping studies: towards a methodological framework. Int J Soc Res Methodol 2005; 8:19–32.

Moura J, Lima M, Nogueira N, Castro M, Lima C, Moura M, Moura L. LSTR Antibiotic paste versus zinc oxide and eugenol pulpectomy for the treatment of primary molars with pulp necrosis: a randomized controlled trial. Pediatric Dentistry 2021; 43(6):435-442.

Rai R, Shashibhushan KK, Babaji P, Chandrappa PM, Reddy VR, Ambareen Z. Clinical and radiographic evaluation of 3mix and vitapex as pulpectomy medicament in primary molars: an in vivostudy. Int J Clin Pediatr Dent 2019; 12(6):532-537.

Lokade A, Thakur S, Singhal P, Chauhan D, Jayam C. Comparative evaluation of clinical and radiographic success of three different lesion sterilization and tissue repair techniques as treatment options in primary molars requiring pulpectomy: An in vivo study. J Indian Soc Pedod Prev Dent 2019; 37:185‑191.

Sijini OT, Sabbagh HJ, Baghlaf KK, Bagher AM, Elâ€housseiny AA, Alamoudi NM, Bagher SM. Clinical and radiographic evaluation of triple antibiotic paste pulp therapy compared to Vitapex pulpectomy in non-vital primary molars. Clin Exp Dent Res 2021; 7(5):819-828.

Thakur S, Deep A, Singhal P, Chauhan D. Randomized control trial comparing the efficacy of 3Mixtatin and Modified 3Mix‑MP paste using lesion sterilization and tissue repair technique to conventional root canal treatment in primary molars of children aged 4–8 years: An in vivo study. Dent Res J 2021; 18:93

Nanda R, Koul M, Srivastava S, Upadhyay V, Dwivedi R. Clinical evaluation of 3 Mix and Other Mix in non-instrumental endodontic treatment of necrosed primary teeth, J Oral Biol Craniofac Res 2014; 4:114-119.

Parakh K, Shetty RM. Evaluation of paste containing gentamicin, amoxicillin and metronidazole in endodontic treatment of primary molars in vivo. Chin J Dent Res 2019; 22:57-64.

de Deus Moura LFAD, de Lima MDM, Lima CCB, Machado JIAG, de Moura MS, de Carvalho PV. Endodontic treatment of primary molars with antibiotic paste: A report of 38 cases. J Clin Pediatr Dent 2016; 40(3):175-177.

Duanduan A, Sirimaharaj V, Chompu-inwai P. Retrospective study of pulpectomy with vitapex® and LSTR with three antibiotics combination (3Mix) for non-vital pulp treatment in primary teeth. Chiang Mai Univ J Nat Sci 2013; 12(2):131–139.

Raslan N, Mansour O, Assfoura L. Evaluation of antibiotic mix in non-instrumentation endodontic treatment of necrotic primary molars. European Journal of Paediatric Dentistry 2017; 18(4):285–290.

Anila B, Murali H, Cheranjeevi J, Kapil RS. Lesion sterilization and tissue repair (LSTR): A review. J Sci Dent 2020; 4(2):49‑55.

Vijayaraghavan R, Mathian VM, Sundaram AM, Karunakaran R, Vinodh S. Triple antibiotic paste in root canal therapy. Journal of Pharmacy & Bioallied Sciences 2012; 4:230-233.

Takushige T, Cruz EV, Asgor MA, Hoshino E. Endodontic treatment of primary teeth using a combination of antibacterial drugs. Int Endod J 2004; 37:132-38

Hoshino. LSTR 3Mix-MP method – better and efficient clinical procedures of lesion sterilization and tissue repair (LSTR) therapy. Dental Rev 2004; 6(4):16-25.

Hoshino E. Sterlization of carious lesions by drugs. J Jap Assoc Dent Sci 1990; 9:32-37.

Takushige T, Cruz EV, Moral AA, Hoshino E. Endodontic treatment of primary teeth using a combination of antibacterial drugs. IntEndod J 2004; 37:132-138.

Burrus D, Barbeau L, Hodgson B. Treatment of abscessed primary molars utilizing lesion sterilization and tissue repair: Literature review and report of three cases. Pediatr Dent 2014; 36:240 244

Mohammadi Z, Abbott PV. On the local applications of antibiotics and antibioticâ€based agents in endodontics and dental traumatology. Int Endod Journ 2009; 42(7):555–567.

Pinky C, Shashibhushan KK, Subbareddy VV. Endodontic treatment of necrosed primary teeth using two different combinations of antibacterial drugs: An in vivo study. J Indian Soc Pedod Prev Dent 2011; 29:121-127.

Cappiello J. Tratamentos pulpares em incisivos primários. [Pulp treatment in primary incisors]. Rev Asoc Odontol Argent 1967; 52(4):139-145

Moulds RFW, Jeyasingham MS. Gentamicin : a great way to start. Australian Prescriber 2011; 33:134-135.

Cruz EV, Kota K, Huque J, Iwaku M, Hoshino E. Penetration of propylene glycol into dentine. Int Endod J 2002; 35:330–336.

Silveira CM, Sánchez Ayala A, Lagravère MO, Pilatti GL, Gomes OM. Repair of furcal perforation with mineral trioxide aggregate: Long term follow up of 2 cases. J Can Dent Assoc 2008; 74:729 33.

Abbott PV, Lin S. Tooth resorption Part 2: A clinical classification. Dental Traumatology 2022; 38:267–285.

Garant, P. 2003. Oral Cell and Tissues. Quintenssence Publishing co Ltd. London

Brustolin JP, Mariath AA, Ardenghi TM, Casagrande L. Survival and factors associated with failure of pulpectomies performed in primary teeth by dental students. Braz Dent J 2017; 28(1):121-128.

Coll JA, Dhar V, Vargas K, Chen CY, Crystal YO, AlShamali S, Marghalani AA. Use of non-vital pulp therapies in primary teeth. Pediatr Dent 2020; 42:337–349.

Trairatvorakul C, Detsomboonrat P. Success rates of a mixture of ciprofloxacin, metronidazole, and minocycline antibiotics used in the non-instrumentation endodontic treatment of mandibular primary molars with carious pulpal involvement. Int J Paediatr Dent 2012; 22:217-227.




DOI: https://doi.org/10.33854/jbd.v11i2.1697

DOI (PDF (Bahasa Indonesia)): https://doi.org/10.33854/jbd.v11i2.1697.g576

Refbacks

  • There are currently no refbacks.


Copyright (c) 2025 Natasha Gamasita

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.