THE MANAGEMENT OF NECROTIZING FASCIITIS IN PATIENT WITH SYSTEMIC LUPUS ERYTHEMATOSUS: A CASE REPORT

Muftihat Israr, Abel Tasman Yuza, Winarno Priyanto

Abstract


Introduction: Necrotizing fasciitis due to odontogenic infection is a serious, rapidly progressive infection that infects the skin and soft tissue and has a high mortality rate, requiring early diagnosis and aggressive treatment. Systemic lupus erythematosus is an autoimmune disease that can predispose to severe odontogenic infections, especially necrotizing fasciitis, and worsens immune response to surgical debridement. Case and Management: A 46 years old female patient with a history of systemic lupus erythematosus was referred to the Emergency Department at Hasan Sadikin General Hospital, Bandung with complaints of swelling accompanied by pain at the chin extended to the right lower jaw region. Clinical examination revealed necrosis of the skin, fluctuations, spontaneous drainage, and crepitations. The patient was diagnosed with necrotizing fasciitis and was underwent necrotizing debridement at submental region and tooth extraction under local anesthesia and administration of broad-spectrum empiric antibiotics, followed by wound care with modern dressings. Immunosuppressant drugs were stopped for three days post treatment. Conclusion: Management of necrotizing fasciitis with necrotizing debridement, extraction of teeth, discontinuation of immunosuppressant, and empiric administration of broad-spectrum antibiotics in patients with Systemic Lupus Erythematosus was necessary to prevent further infection to other fascia.

Keywords


necrotizing fasciitis, necrotomy debridement, odontogenic infection, systemic lupus erythematosus

References


Chou PY, Hsieh YH, Lin CH. Necrotizing fasciitis of the entire head and neck: Literature review and case report. Biomed J. 2020;43:94–8.

Srinivas SM, Patil AT, Shankar G, Lakshmikantha KM, Govindraj M. Necrotizing fasciitis associated with systemic lupus erythematosus in a child. Indian Dermatol Online J. 2015;6:441–2.

He J, Li Z. Dilemma of immunosuppression and infection risk in systemic lupus erythematosus. Rheumatology. 2023;62:i22–9.

Kedves M, Kósa F, Kunovszki P, Takács P, Szabó MZ, Karyekar C, et al. Large-scale mortality gap between SLE and control population is associated with increased infection-related mortality in lupus. Rheumatology. 2020;59:3443–51.

Chang GH, Su YC, Lin KM, Liu CY, Yang YH, Chang PJ, et al. Deep Neck Infection in Systemic Lupus Erythematosus Patients: Real-World Evidence. Sci Rep. 2020;10:4133.

Böttger S, Zechel-Gran S, Schmermund D, Streckbein P, Wilbrand JF, Knitschke M, et al. Odontogenic Cervicofacial Necrotizing Fasciitis: Microbiological Characterization and Management of Four Clinical Cases. Pathogens. 2022;11:78.

Ahmadzada S, Rao A, Ghazavi H. Necrotizing fasciitis of the face: current concepts in cause, diagnosis and management. Curr Opin Otolaryngol Head Neck Surg. 2022;30:270–5.

Yu X, Guo Z, Zhang M, Fu Q, Zhou J. Clinical analysis of diagnosis and treatment of necrotizing fasciitis. Eur J Inflamm. 2022;20:1721727X221141822.

Shetty D, Desai A, Kumar N. Necrotizing fasciitis of the face: the flesh eating catastrophic malady. Malta Med J. 2022;34:102–6.

Gore MR. Odontogenic necrotizing fasciitis: a systematic review of the literature. BMC Ear Nose Throat Disord. 2018;18:14.

Chen LL, Fasolka B, Treacy C. Necrotizing fasciitis: A comprehensive review. Nursing (Lond). 2020;50:34–40.

Hernández DAA, Chávez AMG, Rivera AS. Facial Necrotizing Fasciitis in Adults. A Systematic Review. Heighpubs Otolaryngol Rhinol. 2017;1:020–31.

Wallace HA, Perera TB. Necrotizing Fasciitis. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023[cited 2023 Jun 1]. Available from: http://www.ncbi.nlm.nih.gov/books/NBK430756/

Owen Kuby Immunology 7th Ed. ( 2013) [Internet]. [cited 2023 Jun 3]. Available from: http://archive.org/details/OwenKubyImmunology7thEd.2013

Yuan Q, Xing X, Lu Z, Li X. Clinical characteristics and risk factors of infection in patients with systemic lupus erythematosus: A systematic review and meta-analysis of observational studies. Semin Arthritis Rheum. 2020;50:1022–39.




DOI: https://doi.org/10.33854/jbd.v11i1.1554

DOI (PDF (Bahasa Indonesia)): https://doi.org/10.33854/jbd.v11i1.1554.g538

Refbacks

  • There are currently no refbacks.


Copyright (c) 2024 Muftihat Israr

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.