THE MANAGEMENT OF NECROTIZING FASCIITIS IN PATIENT WITH SYSTEMIC LUPUS ERYTHEMATOSUS: A CASE REPORT
DOI:
https://doi.org/10.33854/jbd.v11i1.1554Keywords:
necrotizing fasciitis, necrotomy debridement, odontogenic infection, systemic lupus erythematosusAbstract
Introduction: Necrotizing fasciitis due to odontogenic infection is a serious, rapidly progressive infection that infects the skin and soft tissue and has a high mortality rate, requiring early diagnosis and aggressive treatment. Systemic lupus erythematosus is an autoimmune disease that can predispose to severe odontogenic infections, especially necrotizing fasciitis, and worsens immune response to surgical debridement. Case and Management: A 46 years old female patient with a history of systemic lupus erythematosus was referred to the Emergency Department at Hasan Sadikin General Hospital, Bandung with complaints of swelling accompanied by pain at the chin extended to the right lower jaw region. Clinical examination revealed necrosis of the skin, fluctuations, spontaneous drainage, and crepitations. The patient was diagnosed with necrotizing fasciitis and was underwent necrotizing debridement at submental region and tooth extraction under local anesthesia and administration of broad-spectrum empiric antibiotics, followed by wound care with modern dressings. Immunosuppressant drugs were stopped for three days post treatment. Conclusion: Management of necrotizing fasciitis with necrotizing debridement, extraction of teeth, discontinuation of immunosuppressant, and empiric administration of broad-spectrum antibiotics in patients with Systemic Lupus Erythematosus was necessary to prevent further infection to other fascia.References
Chou PY, Hsieh YH, Lin CH. Necrotizing fasciitis of the entire head and neck: Literature review and case report. Biomed J. 2020;43:94–8.
Srinivas SM, Patil AT, Shankar G, Lakshmikantha KM, Govindraj M. Necrotizing fasciitis associated with systemic lupus erythematosus in a child. Indian Dermatol Online J. 2015;6:441–2.
He J, Li Z. Dilemma of immunosuppression and infection risk in systemic lupus erythematosus. Rheumatology. 2023;62:i22–9.
Kedves M, Kósa F, Kunovszki P, Takács P, Szabó MZ, Karyekar C, et al. Large-scale mortality gap between SLE and control population is associated with increased infection-related mortality in lupus. Rheumatology. 2020;59:3443–51.
Chang GH, Su YC, Lin KM, Liu CY, Yang YH, Chang PJ, et al. Deep Neck Infection in Systemic Lupus Erythematosus Patients: Real-World Evidence. Sci Rep. 2020;10:4133.
Böttger S, Zechel-Gran S, Schmermund D, Streckbein P, Wilbrand JF, Knitschke M, et al. Odontogenic Cervicofacial Necrotizing Fasciitis: Microbiological Characterization and Management of Four Clinical Cases. Pathogens. 2022;11:78.
Ahmadzada S, Rao A, Ghazavi H. Necrotizing fasciitis of the face: current concepts in cause, diagnosis and management. Curr Opin Otolaryngol Head Neck Surg. 2022;30:270–5.
Yu X, Guo Z, Zhang M, Fu Q, Zhou J. Clinical analysis of diagnosis and treatment of necrotizing fasciitis. Eur J Inflamm. 2022;20:1721727X221141822.
Shetty D, Desai A, Kumar N. Necrotizing fasciitis of the face: the flesh eating catastrophic malady. Malta Med J. 2022;34:102–6.
Gore MR. Odontogenic necrotizing fasciitis: a systematic review of the literature. BMC Ear Nose Throat Disord. 2018;18:14.
Chen LL, Fasolka B, Treacy C. Necrotizing fasciitis: A comprehensive review. Nursing (Lond). 2020;50:34–40.
Hernández DAA, Chávez AMG, Rivera AS. Facial Necrotizing Fasciitis in Adults. A Systematic Review. Heighpubs Otolaryngol Rhinol. 2017;1:020–31.
Wallace HA, Perera TB. Necrotizing Fasciitis. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023[cited 2023 Jun 1]. Available from: http://www.ncbi.nlm.nih.gov/books/NBK430756/
Owen Kuby Immunology 7th Ed. ( 2013) [Internet]. [cited 2023 Jun 3]. Available from: http://archive.org/details/OwenKubyImmunology7thEd.2013
Yuan Q, Xing X, Lu Z, Li X. Clinical characteristics and risk factors of infection in patients with systemic lupus erythematosus: A systematic review and meta-analysis of observational studies. Semin Arthritis Rheum. 2020;50:1022–39.
Downloads
Published
Issue
Section
License
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).


